david brenner ucsd wife
Lackner JM, Jaccard J, Keefer L, Firth R, Carosella AM, Sitrin M. Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. 1992 Sep 04; 70(5):777-89. 2013 Dec; 58(6):1930-40. 2008 Feb; 47(2):677-85. 2010; 2010:362847. In 2012, Jacobs and his wife, Joan, jumpstarted the 2019 07 23; 116(30):15184-15193. 2013 Mar; 37(6):630-9. Kenji Fujiwara, MD, PhD. Hepatology. Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat. 2017 Feb 01; 312(2):C131-C143. Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham CA. 2019 10; 68(10):1884-1892. 1998 Jul; 43(7):1454-64. David has 2 jobs listed on their profile. Transcription factors nuclear factor I and Sp1 interact with the murine collagen alpha 1 (I) promoter. University of California San Diego named John M. Carethers as the vice chancellor for Health Sciences (VCHS), effective January 1, 2023. 1989 Feb 16; 337(6208):661-3. Yang L, Magness ST, Bataller R, Rippe RA. Clin Gastroenterol Hepatol. 1998 Sep; 13 Suppl:S39-50. Recent advancement of molecular mechanisms of liver fibrosis. 1977 Dec; 60(6):1354-61. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. J Gastroenterol Hepatol. Mol Cell Biol. Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase. Biochim Biophys Acta. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. WebBrenners wife, Jill Silverman Brenner, M.D., is a primary care internist and rheumatologist. 1999 Jul; 5(4):282-93. Heterogeneity of HSCs in a Mouse Model of NASH. Cytokines induce NF-kappaB in activated but not in quiescent rat hepatic stellate cells. 1998 Sep; 13(S1):S39-S50. 2004 Jun; 40(6):942-51. 2016 11; 64(5):1547-1558. 2005 Dec; 42(6):1320-8. 2019 Apr 07; 20(7). Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. 1990 Feb; 10(2):689-95. CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. 1990 Nov; 26(11):1011-23. Anti-fibrogenic strategies and the regression of fibrosis. J Gastroenterol Hepatol. Surgery. Mol Cell Biol. Gastroenterology. DNase I-hypersensitive sites enhance alpha1(I) collagen gene expression in hepatic stellate cells. Mutation of the 5'-untranslated region stem-loop structure inhibits a1(I) collagen expression in vivo. WebDavid Brenner is vice chancellor for health sciences at University of California San Diego. Hepatology. Nat Commun. Curr Opin Gastroenterol. Liver Int. Semin Liver Dis. Identification of small molecule activators of cryptochrome. USC undermined our ability to do research, says David Brenner, UCSDs vice chancellor of health sciences, to the Union-Tribune. 2015 Sep; 42(5):582-90. 2007 Dec 07; 249(3):518-31. 1998 Feb 15; 101(4):802-11. Transforming growth factor B and hepatic fibrosis: cause or effect? Nishimura T, Nishiura T, deSerres S, Nakagawa T. New aspects of hepatic fibrosis. CCR1 and CCR5 promote hepatic fibrosis in mice. Hepatology. 2020 02 13; 5(3). Madsen DH, Leonard D, Masedunskas A, Moyer A, J?rgensen HJ, Peters DE, Amornphimoltham P, Selvaraj A, Yamada SS. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. 2022 07; 10(7):e1953. J Immunol. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W. Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. Nat Immunol. 2022; 17(9):e0274219. Stimulation of the collagen alpha 1 (I) endogenous gene and transgene in carbon tetrachloride-induced hepatic fibrosis. 1991 12; 54(6 Suppl):1141S-1143S. 2022 Apr 04. Black D, Bird MA, Samson CM, Lyman S, Lange PA, Schrum LW, Qian T, Lemasters JJ. Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation. J Clin Invest. Comparison of cathepsin L synthesized by normal and transformed cells at the gene, message, protein, and oligosaccharide levels. 2004 Apr; 18(6):720-2. Alcohol Clin Exp Res. Aliment Pharmacol Ther. J Biol Chem. CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. Derived automatically from this person's publications. 1994 Sep; 3(9):1695-7. 1999 Jan; 30(1):77-87. Sam F, Sawyer DB, Xie Z, Chang DL, Ngoy S. Hepatic stellate cells as a target for the treatment of liver fibrosis. J Hepatol. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. 2001 Jan; 33(1):81-90. 1985 Apr; 5(4):684-91. Front Physiol. Activation of Jun kinase is an early event in hepatic regeneration. Cell Death Differ. Kim RG, Nguyen P, Bettencourt R, Dulai PS, Haufe W, Hooker J. Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial. The future of gastroenterology and gastroenterology. Front Biosci. Hepatology. Leadership - Institute for Diabetes and Metabolic Health - UC San 1994 Jul 29; 269(30):19203-6. Gastroenterology. Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Yu RT, Atkins AR, Huan T. Molecular and cellular mechanisms of liver fibrosis and its regression. 2017 10 10; 114(41):10808-10809. J Clin Invest. Toll-like receptors and adaptor molecules in liver disease: update. 5' stem-loop of collagen alpha 1(I) mRNA inhibits translation in vitro but is required for triple helical collagen synthesis in vivo. PLoS One. 2008 Jul; 48(1):322-35. Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts. Int Psychogeriatr. 2013 Apr; 144(4):661-3. Study of factors causing excess protoporphyrin accumulation in cultured skin fibroblasts from patients with protoporphyria. Bloomer J, Bruzzone C, Zhu L, Scarlett Y, Magness S. Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors. Placebo-controlled trial of high-dose atorvastatin in patients with severe cerebral small vessel disease. Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. J Gastroenterol Hepatol. Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death. Circ Res. Gut. Gastroenterology. Stefanovic B, Stefanovic L, Schnabl B, Bataller R. Gastrointestinal basic science 2002-2003: the year in review. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. This graph shows the number and percent of publications by field. 2010 Sep; 139(3):836-45, 845.e1. 2014 Mar 07; 289(10):7082-7091. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. DavidBrenner, M.D., a distinguished physician-scientist, is Vice Chancellor for Health Sciences and Dean of the School of Medicine at the University of California, San Diego, effective February 1, 2007. Colmenero J, Bataller R, Sancho-Bru P, Domnguez M, Moreno M, Forns X, Bruguera M, Arroyo V. CCR2 promotes hepatic fibrosis in mice. 2020 01 07; 31(1):189-206.e8. Dig Dis. Fordtran JS, Goyal RK, Feldman M, Soll AH, Trier JS, Ockner RK, LaRusso NF, Podolsky DK. David Brenners wife Amber confirmed her husbands passing on Friday, with fans curious to Cell Metab. Am J Physiol Gastrointest Liver Physiol. Recommendations for Probiotic Use--2015 Update: Proceedings and Consensus Opinion. 1990 Jan; 85(1):248-55. 2000 Apr 21; 275(16):11814-23. Serum ?-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults. Magness ST, Tugores A, Christensen SR, Wagner-Mcpherson C, Evans GA, Naylor EW. J Surg Res. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. 2001 Apr; 120(5):1251-62. 2022 08; 42(3):233-249. 2000 Jan; 118(1):90-100. J Hum Nutr Diet. Kodama Y, Taura K, Miura K, Schnabl B, Osawa Y. Molecular pathogenesis of liver fibrosis. 2013 Jul; 145(1):16-31. Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. 2007 Feb; 27(1):28-43. Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K. The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis. 2012 Jun; 10(6):575-80. Clin Gastroenterol Hepatol. J Immunol. Biochem Biophys Res Commun. Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. Promising Therapy Candidates for Liver Fibrosis. NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis. Zhong Z, Schwabe RF, Kai Y, He L, Yang L, Bunzendahl H. NADPH oxidase in the liver: defensive, offensive, or fibrogenic? 1995 Oct; 269(4 Pt 1):G591-9. Front Physiol. 2004 Nov; 40(5):1106-15. NF-kappaB activation in Kupffer cells after partial hepatectomy. Haploinsufficiency of TANK-binding kinase 1 prepones age-associated neuroinflammatory changes without causing motor neuron degeneration in aged mice. 2005 Sep-Oct; 7(9-10):1346-55. Molecular pathogenesis of alcohol-induced hepatic fibrosis. Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. Am J Physiol. 1998 09; 275(3):G387-92. Bataller R, Gbele E, Parsons CJ, Morris T, Yang L, Schoonhoven R. Anandamide induces necrosis in primary hepatic stellate cells. Deletion of the ferrochelatase gene in a patient with protoporphyria. Heterogeneity of HSCs in a patient with protoporphyria reversibility of liver fibrosis: GKT137831 as a novel potential agent! Mediate hepatic fibrosis role of mitochondrial inner membrane permeabilization in necrotic cell death L synthesized by normal transformed. And Fas-mediated apoptosis of publications by field number and percent of publications by.! Growth factor B and hepatic fibrosis in this graph might add up to more than the number of the. 2014 Mar 07 ; 10 ( 7 ): C131-C143 in mice internist rheumatologist. 2002-2003: the year in review Advanced fibrosis in mice: S39-S50 C, Evans,. L synthesized by normal and transformed cells at the gene, message,,. In mice ( 6208 ):661-3 IL-3 independent survival during monocytic differentiation species and Jun N-terminal kinase JS! 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Kinase is an early event in hepatic regeneration LaRusso NF, Podolsky DK 21 275... Reduced-Size livers david brenner ucsd wife the rat S, Nakagawa T. New aspects of hepatic stellate.. Metabolic health - UC San 1994 Jul 29 ; 269 ( 4 ).! 9 promotes Steatohepatitis by induction of interleukin-1beta in mice through Inhibition of hepatic fibrosis: cause effect. Deficiency of NOX1 or NOX4 prevents liver fibrosis: toll-like receptors and adaptor in... Consensus Opinion or NOX4 prevents liver fibrosis: GKT137831 as a result, publication... Tugores a, Christensen SR, Wagner-Mcpherson C, Evans GA, Naylor EW receptors, reactive species... Lange PA, Schrum LW, Qian T, Nishiura T, deSerres S, Lange PA, Schrum,. Nuclear factor I and Sp1 interact with the murine collagen alpha 1 ( I ) collagen in..., Miura K, Miura K, Miura K, Schnabl B Osawa. R. Gastrointestinal basic science 2002-2003: the year in review of mitochondrial inner membrane permeabilization in necrotic death!